Phase I study of procaspase-activating compound-1 (PAC-1) in the treatment of advanced malignancies
Oana C. Danciu, Matthias Holdhoff, Richard A. Peterson, James H. Fischer, Li Liu, Heng Wang, Neeta K. Venepalli, Rozina A. Chowdhery, M. Kelly Nicholas, Meredith Jones Russell, Timothy M. Fan, Paul J. Hergenrother, Theodore M. Tarasow, Arkadiusz Z. Dudek
Topics & Concepts
MedicinePharmacokineticsAdverse effectDosingToxicityPharmacologyRefractory (planetary science)Internal medicineMaximum tolerated doseOncologyAstrobiologyPhysicsCell death mechanisms and regulationNeuroendocrine Tumor Research AdvancesProtein Kinase Regulation and GTPase Signaling