Bacteriophages as nanocarriers for targeted drug delivery and enhanced therapeutic effects
Stephen Chijioke Emencheta, Adaeze Linda Onugwu, Chisom F. Kalu, Patience N. Ezinkwo, Osita C. Eze, Marta M. D. C. Vila, Victor M. Balcão, Anthony A. Attama, Ebele Onuigbo
Abstract
The bioengineering of phages to display ligands leads to specific targeting, reduced toxicity, enhanced cellular uptake of an incorporated drug/gene and, ultimately, increased therapeutic efficacy.
Topics & Concepts
NanocarriersDrug deliveryDrugTargeted drug deliveryMedicinePharmacologyTherapeutic indexNanotechnologyMaterials scienceBacteriophages and microbial interactions