Host cell proteins induce inflammation and immunogenicity as adjuvants in an integrated analysis of in vivo and in vitro assay systems
Kyohei Yasuno, Eri Hamamura-Yasuno, Daisuke Nishimiya, Masako Soma, Masako Imaoka, Kiyonori Kai, Kazuhiko Mori
Topics & Concepts
ImmunogenicityIn vivoIntravitreal administrationRanibizumabMedicineIn vitroAdjuvantPharmacologyInflammationCellAntigenImmune systemImmunologyChemistryBiologyInternal medicineOphthalmologyRetinalBiochemistryChemotherapyBevacizumabBiotechnologyProtein purification and stabilityMonoclonal and Polyclonal Antibodies ResearchAdvanced Drug Delivery Systems