Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation
David Castel, Thomas Kergrohen, Arnault Tauziède‐Espariat, Alan Mackay, Samia Ghermaoui, Emmanuèle Lechapt, Stefan M. Pfister, Christof M. Kramm, Nathalie Boddaert, Thomas Blauwblomme, Stéphanie Puget, Kévin Beccaria, Chris Jones, David Jones, Pascale Varlet, Jacques Grill, Marie‐Anne Debily
Topics & Concepts
Histone H3Cancer researchMutationHistonePRC2BiologyChemistryMedicineMolecular biologyGeneticsDNAGeneGlioma Diagnosis and TreatmentEpigenetics and DNA MethylationChromatin Remodeling and Cancer