Potential value of Interleukin-6 as a diagnostic biomarker in human MDD and the antidepressant effect of its receptor antagonist tocilizumab in lipopolysaccharide-challenged rats
Dandan Xu, Yayun Xu, Xinran Gao, Mengyu Yan, Chen Zhang, Xian Wu, Qingrong Xia, Jin‐Fang Ge
Topics & Concepts
TocilizumabInternal medicineMedicineAntidepressantInterleukin 6EndocrinologyHamdBehavioural despair testReceptor antagonistAntagonistTumor necrosis factor alphaInterleukin 1 receptor antagonistInterleukinLipopolysaccharideHippocampusReceptorCytokineDiseaseSignificant differenceTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms