Diagnosis of <i>Mycobacterium tuberculosis</i> using palladium–platinum bimetallic nanoparticles combined with paper-based analytical devices
C.Y. Tung, Tsung‐Ting Tsai, Ping-Yeh Chiu, Roman Viter, Arūnas Ramanavičius, Cheng‐Ju Yu, Chien‐Fu Chen
Abstract
on a paper-based analytical device. With the above-mentioned method, we can detect target DNA within 15 minutes with a linear range between 0.75 and 10 nM, and a detection limit of 0.216 nM. These results demonstrate that the proposed platform (a DNA-nanozyme integrated paper-based analytical device, dnPAD) can provide sensitive and on-site infection prognosis in areas with insufficient medical resources.
Topics & Concepts
Bimetallic stripPlatinumPalladiumMycobacterium tuberculosisMaterials scienceTuberculosisNanoparticleNanotechnologyCatalysisChemistryMedicineMetallurgyOrganic chemistryMetalPathologyBiosensors and Analytical DetectionAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniques