AhR-mediated CYP1A1 and ROS overexpression are involved in hepatotoxicity of decabromodiphenyl ether (BDE-209)
Jinwen Yuan, Xiaoming Sun, Siyan Che, Li Zhang, Zheng Ruan, Xiaomin Li, Junhua Yang
Topics & Concepts
ChemistryGlutathioneAryl hydrocarbon receptorReactive oxygen speciesPolybrominated diphenyl ethersDecabromodiphenyl etherSuperoxide dismutaseAntioxidantOxidative stressDiphenyl etherPharmacologyBiochemistryPollutantEnzymeBiologyFire retardantOrganic chemistryTranscription factorGeneToxic Organic Pollutants ImpactAir Quality and Health ImpactsCarcinogens and Genotoxicity Assessment