Regulatory mechanisms and therapeutic implications of insulin-like growth factor 2 mRNA-binding proteins, the emerging crucial m<sup>6</sup>A regulators of tumors
Heng Zhou, Qiang Sun, Ming-Liang Feng, Ziming Gao, Shiheng Jia, Lanxin Cao, Xue Yu, Shan Gao, Huizhe Wu, Kai Li
Abstract
A readers in the context of tumor pathogenesis and multidrug resistance. Furthermore, we highlight the potential of IGF2BPs as drug targets in clinical tumor treatment. Hence, precise and novel tumor therapeutic approaches could be uncovered by targeting epigenetic heterogeneity.
Topics & Concepts
EpigeneticsBiologyCarcinogenesisTranslation (biology)Context (archaeology)RNA-binding proteinRNAMechanism (biology)Messenger RNACancer researchCell biologyComputational biologyBioinformaticsCancerGeneticsGenePaleontologyPhilosophyEpistemologyRNA modifications and cancerCancer-related molecular mechanisms researchRNA Research and Splicing