Magnetic-enhanced fluorescence sensing of tumor miRNA by combination of MNPs@PDA with duplex specific nuclease
Yujie Sun, Cancan Wang, Lina Tang, Yulin Zhang, Guojun Zhang
Abstract
the recycling process. The established method achieved a low detection limit down to 0.42 pM. The linear concentration range was from 5 pM to 5 nM. Moreover, this method also had high specificity. Remarkably, the target miRNAs extracted from human cells were detected by using the sensing platform.
Topics & Concepts
NucleaseDuplex (building)FluorescenceMagnetic nanoparticlesBiosensorChemistryNanoparticlemicroRNANanotechnologyMaterials scienceBiophysicsDNABiochemistryBiologyPhysicsGeneOpticsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry