Antibacterial, wet adhesive, and healing-promoting nanosheets for the treatment of oral ulcers
Haijun Fu, Jiayu Yang, Zongshan Shen, Yong Zhang, Shuhong Kuang, Lifeng Li, Zhengmei Lin, Xuetao Shi
Abstract
. Furthermore, APCNs treatment accelerated ulcer healing in a Sprague Dawley rat oral ulcer model. Our study developed antibacterial, wet-adhesive, and healing-promoting PCL-collagen nanosheets and demonstrated that these nanosheets could be promising adhesive therapeutic agents for the treatment of oral mucosal ulcers.
Topics & Concepts
AdhesiveAntibacterial activityAdhesionAntimicrobialBioadhesiveChemistryDrugBiocompatibilitySalivaWound healingMicrobiologyPharmacologyBacteriaMedicineLayer (electronics)SurgeryBiochemistryDrug deliveryBiologyOrganic chemistryGeneticsAntimicrobial Peptides and ActivitiesPeriodontal Regeneration and TreatmentsSilk-based biomaterials and applications