Three genomes in the algal genus <i>Volvox</i> reveal the fate of a haploid sex-determining region after a transition to homothallism
Kayoko Yamamoto, Takashi Hamaji, Hiroko Kawai‐Toyooka, Ryo Matsuzaki, Fumio Takahashi, Yoshiki Nishimura, Masanobu Kawachi, Hideki Noguchi, Yohei Minakuchi, James Umen, Atsushi Toyoda, Hisayoshi Nozaki
Abstract
Significance Evolutionary transitions between species with separate sexes and species in which individuals have both sex functions have wide-ranging biological implications. It is largely unknown how such transitions occur in systems with haploid male- and female-determining chromosomes in algae and bryophytes. We investigated such a transition in the algal genus Volvox by making whole-genome sequences of two closely related species, one of which is heterothallic (with distinct males and females) and the other homothallic (with only bisexual, self-compatible individuals). The heterothallic species harbors a sex-determining region (SDR), while the homothallic species retains a nearly intact female-derived SDR-like region and separate regions containing key male genes. Thus, an ancestral female has probably become homothallic by acquiring genes that confer male functions.