Insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis
Dat P. Ha, Amy S. Lee
Topics & Concepts
PI3K/AKT/mTOR pathwayDownregulation and upregulationCell biologyProtein kinase BRegulatorSignal transductionBiologyATF4Unfolded protein responseChemistryEndoplasmic reticulumBiochemistryGeneEndoplasmic Reticulum Stress and DiseasePancreatic function and diabetesGenetics, Aging, and Longevity in Model Organisms