Quaternized carbon dots with enhanced antimicrobial ability towards Gram-negative bacteria for the treatment of acute peritonitis caused by <i>E. coli</i>
Xintian Zhang, Pingping Wu, Xiaoli Hao, Jiamiao Liu, Zhengjun Huang, Shaohuang Weng, Weifeng Chen, Lingling Huang, Jianyong Huang
Abstract
. Routine blood examination, magnetic resonance imaging, and pathological analysis were undertaken and it was found that, similar to the positive control group treated with gentamicin sulfate, the QCDs exhibited a therapeutic effect that eliminated infection and inflammation. This study explores a controllable synthetic strategy for the synthesis of active carbon dots with antibacterial activity, a material that is a promising candidate for new treatments of Gram-negative bacterial infections.
Topics & Concepts
BacteriaAntibacterial activityAntimicrobialGram-positive bacteriaGram-negative bacteriaMicrobiologyHemolysisChemistryMaterials scienceNuclear chemistryMedicineBiologyBiochemistryEscherichia coliImmunologyGeneGeneticsCarbon and Quantum Dots ApplicationsQuantum Dots Synthesis And PropertiesAdvanced Drug Delivery Systems