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Group SELFIES: a robust fragment-based molecular string representation

Austin H. Cheng, Andy Cai, Santiago Miret, Gustavo Malkomes, Mariano Phielipp, Alán Aspuru‐Guzik

2023Digital Discovery65 citationsDOIOpen Access PDF

Abstract

Group SELFIES is a molecular string representation that incorporates tokens which represent substructures while maintaining robustness, which improves the performance of molecular generative models.

Topics & Concepts

Robustness (evolution)Computer scienceRepresentation (politics)Fragment (logic)Generative modelGenerative grammarTheoretical computer scienceArtificial intelligenceChemistryAlgorithmBiochemistryGenePolitical scienceLawPoliticsComputational Drug Discovery MethodsMachine Learning in Materials ScienceChemical Synthesis and Analysis
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