A battery of tandem mass spectrometry assays with stable isotope-dilution for the quantification of 15 anti-tuberculosis drugs and two metabolites in patients with susceptible-, multidrug-resistant- and extensively drug-resistant tuberculosis
Thomas Mercier, Vincent Desfontaine, S. Cruchon, J.A. Da Silva Pereira Clara, Myriam Briki, Jesica Mazza‐Stalder, A. Kajkus, Raphaël Burger, V. Suttels, Thierry Buclin, Onya Opota, Natalia Koehler, Patricia M. Sanchez Carballo, Christoph Lange, Patrice André, Laurent A. Décosterd, Eva Choong
Topics & Concepts
ChemistryProtein precipitationChromatographyEthambutolPyrazinamideRifampicinIsoniazidMoxifloxacinTandem mass spectrometryTherapeutic drug monitoringPharmacokineticsCycloserinePharmacologyMass spectrometryTuberculosisAntibioticsMedicineBiochemistryPathologyTuberculosis Research and EpidemiologyMetabolomics and Mass Spectrometry StudiesPneumocystis jirovecii pneumonia detection and treatment