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Metabolism and Toxicity of Fluorine Compounds

Jillian L. Kyzer, Marvin Martens

2021Chemical Research in Toxicology65 citationsDOIOpen Access PDF

Abstract

Fluorine has many beneficial features and applications but can cause toxicity at high doses. Herein, we describe its chemical properties and benefits to agrochemical design as well as potential metabolic liabilities and exposure assessment in vivo.

Topics & Concepts

ToxicityChemistryAgrochemicalFluorineIn vivoMetabolismPharmacologyEnvironmental chemistryToxicologyBiochemistryOrganic chemistryBiologyBiotechnologyEcologyAgricultureFluorine in Organic ChemistryAmino Acid Enzymes and MetabolismSulfur Compounds in Biology
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