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The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species

Timothy P. L. Smith, Derek M. Bickhart, Didier Boichard, Amanda J. Chamberlain, Appolinaire Djikeng, Yu Jiang, Wai Yee Low, Hubert Pausch, S. Demyda‐Peyrás, James Prendergast, Robert D. Schnabel, Benjamin D. Rosen

2023Genome biology59 citationsDOIOpen Access PDF

Abstract

The Bovine Pangenome Consortium (BPC) is an international collaboration dedicated to the assembly of cattle genomes to develop a more complete representation of cattle genomic diversity. The goal of the BPC is to provide genome assemblies and a community-agreed pangenome representation to replace breed-specific reference assemblies for cattle genomics. The BPC invites partners sharing our vision to participate in the production of these assemblies and the development of a common, community-approved, pangenome reference as a public resource for the research community ( https://bovinepangenome.github.io/ ). This community-driven resource will provide the context for comparison between studies and the future foundation for cattle genomic selection.

Topics & Concepts

BiologyContext (archaeology)GenomeGenomicsBovine genomeBreedSelection (genetic algorithm)Computational biologyBiotechnologyGeneticsGeneComputer scienceArtificial intelligencePaleontologyGenetic and phenotypic traits in livestockGenomics and Phylogenetic StudiesCancer-related molecular mechanisms research
The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species | Litcius