Coupling of thiols and aromatic halides promoted by diboron derived super electron donors
Mário Franco, Emily L. Vargas, Mariola Tortosa, M. B. Cid
Abstract
1 mechanism. The reaction is efficient for a broad substrate scope, tolerating heterocycles including pyridines, enolizable or reducible functional groups. The method has been applied to intermediates in drug synthesis as well as interesting functionalized polythioethers through a controlled and consecutive intramolecular electron transfer process.
Topics & Concepts
Radical-nucleophilic aromatic substitutionHalideChemistryIntramolecular forcePyridineCoupling (piping)Combinatorial chemistryPhotochemistrySubstrate (aquarium)Electron transferNucleophilic aromatic substitutionComputational chemistryOrganic chemistryNucleophilic substitutionMaterials scienceOceanographyMetallurgyGeologySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsChemical Synthesis and Reactions