Visible-Light-Induced Esterification of Carboxylic Acids with Arylsulfonium Salts
Fang Xia, Cheng‐Pan Zhang
Abstract
A photoinduced copper-mediated acyloxylation of arylthianthrenium or arylphenoxathiinium salts with either aliphatic or aromatic carboxylic acids is described for the convenient synthesis of O -aryl esters. The reaction has shown obvious advantages, such as high efficiency, good functional group tolerance, excellent chemoselectivity, and capacity for esterification of complex drug molecules, offering a practical synthetic route to multifunctionalized and sterically congested O -aryl esters, which are potentially useful in the development of new prodrugs or twin drugs.
Topics & Concepts
ChemistryCarboxylic acidVisible spectrumOrganic chemistryOptoelectronicsPhysicsRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods