Development and evaluation of protamine-coated PLGA nanoparticles for nose-to-brain delivery of tacrine: In-vitro and in-vivo assessment

Khaled S. Shamarekh, Heba A. Gad, Mahmoud E. Soliman, Omaima A. Sammour

2020Journal of Drug Delivery Science and Technology41 citationsDOI

Topics & Concepts

Nasal administrationPLGATacrineBioavailabilityIn vivoMaterials sciencePharmacologyIn vitroChemistryEx vivoDispersityNuclear chemistryNanoparticleBiomedical engineeringNanotechnologyMedicinePolymer chemistryBiochemistryAcetylcholinesteraseBiologyEnzymeBiotechnologyAdvanced Drug Delivery SystemsOcular Surface and Contact LensAdvancements in Transdermal Drug Delivery