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Excess Mortality in COVID-19-Positive Versus COVID-19-Negative Inpatients With Diabetes: A Nationwide Study

Elias K. Spanakis, Ashley Yoo, Oluwagbemiga Ajayi, Tariq Siddiqui, Mohd Washid Khan, Stephen L. Seliger, David C. Klonoff, Zhaoyong Feng, John D. Sorkin

2021Diabetes Care13 citationsDOIOpen Access PDF

Abstract

Diabetes is a major risk factor for death in those with coronavirus disease 2019 (COVID-19) infection (1). However, even those with diabetes who do not have a COVID-19 infection have an increased risk for mortality compared with those without diabetes (2). In the current study, we focused on hospitalized patients with diabetes and compared those who tested positive for COVID-19 infection to those who tested negative. Our aim was to identify the excess risk of mortality that COVID-19 infection adds among inpatients with diabetes and to assess if this increased mortality can be explained by underlying comorbidities/complications or if it is more closely related to the COVID-19 disease.

Topics & Concepts

MedicineDiabetes mellitusPrediabetesCoronavirus disease 2019 (COVID-19)Internal medicineVeterans AffairsRetrospective cohort studyMetforminRisk factorDiseaseEmergency medicineIntensive care medicineType 2 diabetesInfectious disease (medical specialty)EndocrinologyCOVID-19 Clinical Research StudiesDiabetes Management and ResearchChronic Disease Management Strategies
Excess Mortality in COVID-19-Positive Versus COVID-19-Negative Inpatients With Diabetes: A Nationwide Study | Litcius