Essential oil of Ligusticum chuanxiong Hort. Regulated P-gp protein and tight junction protein to change pharmacokinetic parameters of temozolomide in blood, brain and tumor
Shuyuan Shuai, Shanshan Liu, Xiaojin Liu, Guosong Zhang, Qin Zheng, Pengfei Yue, Ming Yang, Pengyi Hu
Topics & Concepts
TemozolomidePharmacokineticsGliomaCmaxPharmacologyBlood–brain barrierIn vivoWestern blotChemistryMedicineCancer researchInternal medicineBiologyBiochemistryCentral nervous systemGeneBiotechnologyBarrier Structure and Function StudiesTraditional Chinese Medicine AnalysisDrug Transport and Resistance Mechanisms