Triterpenoids with modified A-ring as modulators of P-gp-dependent drug-resistance in cancer cells
Ekaterina Yu. Rybalkina, Н. И. Моисеева, А. Ф. Карамышева, Daria V. Eroshenko, Anastasia V. Konysheva, Alexei V. Nazarov, Victoria V. Grishko
Topics & Concepts
Rhodamine 123CytotoxicityK562 cellsChemistryDoxorubicinP-glycoproteinEffluxCell cultureMultiple drug resistanceCancer cellCytotoxic T cellATP-binding cassette transporterBiochemistryStereochemistryPharmacologyTransporterBiologyCellCancerIn vitroGeneChemotherapyAntibioticsGeneticsDrug Transport and Resistance MechanismsHIV/AIDS drug development and treatmentMetal complexes synthesis and properties