Site‐specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling
Lilian M. Fennell, Carlos Gómez-Díaz, Luiza Deszcz, Anoop Kavirayani, David Hoffmann, Kota Yanagitani, Alexander Schleiffer, Karl Mechtler, Astrid Hagelkrüys, Josef Penninger, Fumiyo Ikeda
Topics & Concepts
BiologyUbiquitin ligaseUbiquitinUbiquitin-Protein LigasesCell biologySignal transductionImmune systemDNA ligaseSignaling proteinsApoptosisGeneticsCancer researchDNAGeneUbiquitin and proteasome pathwaysProtein Degradation and Inhibitorsinterferon and immune responses