What Is the Predictive Value of a Single Nasopharyngeal SARS-CoV-2 PCR Swab Test in a Patient With COVID-Like Symptoms and/or Significant COVID-19 Exposure?
Blessen George, James P. McGee, Eileen Giangrasso, Sheila Finkelstein, Susan Wu, Aaron E. Glatt
Abstract
Utilizing results of polymerase chain reaction (PCR) testing and subsequent antibody titers, we report on the test characteristics of a PCR screening test for severe acute respiratory syndrome coronavirus 2 among hospital workers. The PCR test was found to be 87% sensitive and 97% specific, with a positive predictive value of 0.98 and a negative predictive value of 0.80.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Predictive valuePcr test2019-20 coronavirus outbreakVirologyTiterPolymerase chain reactionPredictive value of testsInternal medicineReal-time polymerase chain reactionBetacoronavirusCoronavirusImmunologyVirusBiologyDiseaseGeneInfectious disease (medical specialty)BiochemistryOutbreakSARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies