Association between non-tea flavonoid intake and risk of type 2 diabetes: the Australian diabetes, obesity and lifestyle study
Mary D. Adu, Catherine P. Bondonno, Benjamin H. Parmenter, Marc Sim, Raymond J. Davey, Kevin Murray, Simone Radavelli‐Bagatini, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno
Abstract
< 0.05 for all), except fasting plasma glucose. During follow-up, 344 incident T2DM cases were recorded. Participants with the highest total flavonoid intake had a 21% lower risk of T2DM over 12 years, although this was not statistically significant in multivariable adjusted models [HR (95% CI): 0.79 (0.57, 1.09)]. This study provides some evidence that consuming flavonoid-rich foods may be protective against T2DM through mechanisms related to glucose tolerance and insulin sensitivity.
Topics & Concepts
MedicineInsulin resistanceDiabetes mellitusType 2 diabetesFlavonoidObesityInternal medicineType 2 Diabetes MellitusInsulinEndocrinologyGlucose homeostasisBiologyBiochemistryAntioxidantPhytochemicals and Antioxidant ActivitiesTea Polyphenols and EffectsNatural Antidiabetic Agents Studies