Free-running circadian breathing rhythms are eliminated by suprachiasmatic nucleus lesion
Benton S. Purnell, Gordon F. Buchanan
Abstract
It has long been appreciated that breathing is altered by time of day. This study demonstrates that rhythmicity in breathing persists in constant darkness but is dependent on the suprachiasmatic nucleus in the hypothalamus. Understanding circadian rhythms in breathing may be important for the treatment and prevention of diseases such as sleep apnea and sudden unexpected death in epilepsy.
Topics & Concepts
Circadian rhythmSuprachiasmatic nucleusTidal volumeVentilation (architecture)Control of respirationBreathingWakefulnessEndocrinologyDark therapySleep and breathingInternal medicineCircadian clockRespiratory systemMedicineBiologyAnesthesiaNeuroscienceElectroencephalographyEngineeringMechanical engineeringCircadian rhythm and melatoninSleep and Wakefulness ResearchNeuroscience of respiration and sleep