Tunneling nanotubes between bone marrow stromal cells support transmitophagy and resistance to apoptosis in myeloma
Antonio Giovanni Solimando, Francesco Di Palma, Vanessa Desantis, Angelo Vacca, Maria Svelto, Francesco Pisani
Abstract
Multiple myeloma (MM) flourishes within the bone marrow (BM), a metabolically unique microenvironment with pronounced spatial oxygen-glucose gradients
Topics & Concepts
Stromal cellBone marrowMultiple myelomaApoptosisMedicineCancer researchHematologyPathologyInternal medicineBiologyGeneticsNanoparticle-Based Drug DeliveryCellular Mechanics and InteractionsMultiple Myeloma Research and Treatments