Re-defining synthetic lethality by phenotypic profiling for precision oncology
Yevhen Akimov, Tero Aittokallio
Topics & Concepts
Synthetic lethalityPrecision oncologyComputational biologyDrug discoveryPhenotypic screeningPhenotypeHigh-throughput screeningScreening techniquesProfiling (computer programming)Identification (biology)LethalityPrecision medicineComputer scienceBiologyBioinformaticsGeneticsGeneDNA repairOperating systemBotanyBioinformatics and Genomic NetworksComputational Drug Discovery MethodsCell Image Analysis Techniques