Litcius/Paper detail

Organising pneumonia manifesting as a late-phase complication of COVID-19

Boon Hau Ng, Bán A, Nik Nuratiqah Nik Abeed, Mohamed Faisal

2021BMJ Case Reports20 citationsDOIOpen Access PDF

Abstract

Acute COVID-19 usually lasts 4 weeks from the onset of symptoms. We report two cases of COVID-19-associated organising pneumonia (OP) occurring beyond 4 weeks from the acute onset of symptoms. Both tested positive for SARS reverse transcription-PCR 2 months before presentation with a resolution of respiratory symptoms. The first case presented with residual fatigue and worsening exertional dyspnoea. Chest CT revealed an OP pattern. The second case presented with worsening cough and new-onset pleuritic chest pain with persistent radiological consolidation. A transbronchial lung biopsy confirmed OP. Both patients responded well to 12 weeks of steroid therapy. This case illustrates the rare presentation of OP as a late sequela of COVID-19 and the good response to steroid therapy.

Topics & Concepts

MedicineSequelaCoronavirus disease 2019 (COVID-19)PneumoniaPresentation (obstetrics)ComplicationChest painRadiological weaponLungPediatricsInternal medicineSurgeryInfectious disease (medical specialty)DiseaseCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19SARS-CoV-2 and COVID-19 Research