Yu Gan Long Ameliorates Hepatic Fibrosis by Inhibiting PI3K/AKT, Ras/ERK and JAK1/STAT3 Signaling Pathways in CCl4-induced Liver Fibrosis Rats
Li Hou-Gang, Pengtao You, Yu Xia, Yu‐Dong Cai, Yijun Tu, Mengheng Wang, Wanci Song, Tai-min Quan, Hui-ying Ren, Liu Yan-wen, Hanxiong Dan, Shiqing Xu
Topics & Concepts
Hepatic stellate cellProtein kinase BPI3K/AKT/mTOR pathwayHepatic fibrosisFibrosisCancer researchDownregulation and upregulationSTAT3Platelet-derived growth factor receptorMAPK/ERK pathwayMedicineCCL4Signal transductionChemistryInternal medicineEndocrinologyGrowth factorCarbon tetrachlorideBiochemistryReceptorGeneOrganic chemistryLiver physiology and pathologyLiver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and Protection