Development of controlled release oral dosages by density gradient modification via three-dimensional (3D) printing and hot-melt extrusion (HME) technology

Zhiqing Hu, Pengchong Xu, Jiaxiang Zhang, Suresh Bandari, Michael A. Repka

2022Journal of Drug Delivery Science and Technology22 citationsDOI

Topics & Concepts

KetoprofenDissolutionMaterials scienceExtrusionAmorphous solidDifferential scanning calorimetryFused deposition modeling3D printingDispersion (optics)Chemical engineeringDosage formComposite materialNanotechnologyChemistryChromatographyOrganic chemistryOpticsPhysicsEngineeringThermodynamics3D Printing in Biomedical ResearchDrug Solubulity and Delivery SystemsAdditive Manufacturing and 3D Printing Technologies