Fudosteine attenuates acute lung injury in septic mice by inhibiting pyroptosis via the TXNIP/NLRP3/GSDMD pathway
Guangming He, Keling Chen, Hao Wang, Xiaoou Li, Wenhao Li, Liu Lian, Jun Chen, Deqing Yang, Jun Hu, Dan Xu, Fuqiang Wen, Tao Wang
Topics & Concepts
PyroptosisTXNIPSepsisProinflammatory cytokineBronchoalveolar lavageMedicineOxidative stressARDSInflammasomePharmacologyLungInflammationImmunologyInternal medicineThioredoxinInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideInflammation biomarkers and pathways