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Neutrophil-to-lymphocyte ratio predicts acute kidney injury occurrence after gastrointestinal and hepatobiliary surgery

Jianbin Bi, Jia Zhang, Yifan Ren, Zhaoqing Du, Zheng Wu, Yi Lv, Rongqian Wu

2020World Journal of Gastrointestinal Surgery28 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Postoperative acute kidney injury (AKI) is a complex pathological process involved intrarenal and systemic inflammation caused by renal hypoperfusion, nephrotoxic drugs and urinary obstruction. Neutrophil-to-lymphocyte ratio (NLR) is a marker of inflammation reflecting the progress of many diseases. However, whether NLR at admission can predict the occurrence of AKI after surgery in the intensive care unit (ICU) remains unknown. AIM: To clarify the relationship between NLR and the occurrence of AKI in patients with gastrointestinal and hepatobiliary surgery in the ICU. METHODS: A retrospective analysis of 282 patients receiving surgical ICU care after gastrointestinal and hepatobiliary surgery in our hospital from December 2014 to December 2018 was performed. RESULTS: = 0.001). CONCLUSION: NLR at admission is a predictor of AKI occurrence in patients with gastrointestinal and hepatobiliary surgery in ICU. NLR should be included in the routine assessment of AKI occurrence.

Topics & Concepts

MedicineAcute kidney injuryNeutrophil to lymphocyte ratioInternal medicineGastroenterologyIntensive care unitRetrospective cohort studyDialysisCohortCreatinineUrinary systemSurgeryLymphocyteAcute Kidney Injury ResearchInflammatory Biomarkers in Disease PrognosisMedical Case Reports and Studies
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