Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System
Gina L. J. Galli, Mitchell C. Lock, Kerri L. M. Smith, Dino A. Giussani, Dane A. Crossley
Abstract
Developmental hypoxia has profound and persistent effects on the vertebrate cardiovascular system, but the nature, magnitude, and long-term outcome of the hypoxic consequences are species specific. Here we aim to identify common and novel cardiovascular responses among vertebrates that encounter developmental hypoxia, and we discuss the possible medical and ecological implications.
Topics & Concepts
VertebrateHypoxia (environmental)BiologyEvolutionary biologyPhysiologyZoologyEcologyGeneticsChemistryOxygenGeneOrganic chemistryBirth, Development, and HealthMitochondrial Function and PathologyAdipose Tissue and Metabolism