Network pharmacology, molecular docking technology integrated with pharmacodynamic study to reveal the potential targets of Schisandrol A in drug-induced liver injury by acetaminophen
Xiankuan Li, Jiaming Ge, Mengyuan Li, Sha Deng, Jiarong Li, Yucong Ma, Jian Zhang, Yanchao Zheng, Lin Ma
Topics & Concepts
AcetaminophenChemistryLiver injuryPharmacologyCYP2E1Drug developmentDrugOxidative stressPharmacodynamicsCytochrome P450BiochemistryPharmacokineticsEnzymeMedicineDrug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug MetabolismEicosanoids and Hypertension Pharmacology