Gene therapy for retinitis pigmentosa
Niloofar Piri, Jacob D. Grodsky, Henry J. Kaplan
Abstract
Rhodopsin-mediated autosomal dominant retinitis pigmentosa (RP) is the most common cause of RP in North America. There is no proven cure for the disease, and multiple approaches are being studied. Gene therapy is an evolving field in medicine and ophthalmology. In this review, we will go over the basic concept of gene therapy and the different types of gene therapy that are currently being studied to treat this disease.
Topics & Concepts
Retinitis pigmentosaMedicineGenetic enhancementDiseaseGeneOphthalmologyBioinformaticsGeneticsInternal medicineRetinalBiologyRetinal Development and DisordersCRISPR and Genetic EngineeringVirus-based gene therapy research