Selective editing of a peptide skeleton <i>via</i> C–N bond formation at N-terminal aliphatic side chains
Yujie Han, Junjie Shi, Songrong Li, Tingting Dan, Wenwen Yang, Mingyu Yang
Abstract
)-H functionalization under visible light. Natural and unnatural amino acids are demonstrated as suitable substrates with the transformations proceeding with excellent regio- and stereo-selectivity.
Topics & Concepts
Side chainTerminal (telecommunication)ChemistrySkeleton (computer programming)StereochemistryPeptideProlineCombinatorial chemistryAmino acidOrganic chemistryComputer scienceBiochemistryPolymerProgramming languageTelecommunicationsChemical Synthesis and AnalysisClick Chemistry and ApplicationsAdvanced biosensing and bioanalysis techniques