Synthesis and antitumor activity of cyclopentane-fused anthraquinone derivatives
Alexander S. Tikhomirov, Yuri B. Sinkevich, Lyubov G. Dezhenkova, Dmitry N. Kaluzhny, Nikolay S. Ilyinsky, Valentin Borshchevskiy, Dominique Schols, Andrey E. Shchekotikhin
Topics & Concepts
ChemistryEffluxLipophilicityCytotoxicityDoxorubicinTopoisomeraseMoietyStereochemistryStructure–activity relationshipCamptothecinIn vitroBiochemistryMedicineChemotherapySurgeryCancer therapeutics and mechanismsSynthesis and Biological EvaluationCancer Treatment and Pharmacology