Pulchinenoside B4 exerts the protective effects against cisplatin-induced nephrotoxicity through NF-κB and MAPK mediated apoptosis signaling pathways in mice
Shuang Wang, Shan Tang, Xuan Chen, Xin Li, Shuang Jiang, Huiping Li, Pin-hui Jia, Mingjie Song, Peng Di, Wei Li
Topics & Concepts
ApoptosisNephrotoxicityPharmacologyCisplatinTumor necrosis factor alphaNitric oxide synthaseMAPK/ERK pathwayKidneyNitric oxideMedicineSignal transductionCancer researchChemistryImmunologyInternal medicineChemotherapyBiochemistryChemotherapy-induced organ toxicity mitigationAcute Kidney Injury ResearchDrug-Induced Hepatotoxicity and Protection