Improved in vitro and in vivo properties of telmisartan in the co-amorphous system with hydrochlorothiazide: A potential drug-drug interaction mechanism prediction
Xiangjun Shi, Xiyue Zhou, Shuimei Shen, Qi‐Feng Chen, Shengjie Song, Chenru Gu, Chao Wang
Topics & Concepts
Amorphous solidHydrochlorothiazideChemistryDrugBioavailabilityTelmisartanIn vivoSolubilityPharmacologyDissolutionPharmaceuticsNuclear chemistryMedicineCrystallographyOrganic chemistryInternal medicineBiotechnologyBiologyBlood pressureDrug Solubulity and Delivery SystemsCrystallization and Solubility StudiesProtein Interaction Studies and Fluorescence Analysis