Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAs
Ping Xu, Zhiheng Liu, Ying Liu, Huazheng Ma, Yiyuan Xu, Ying Bao, Shiyou Zhu, Zhongzheng Cao, Zeguang Wu, Zhuo Zhou, Wensheng Wei
Topics & Concepts
InterrogationComputational biologyGeneBiologyGenomeBase (topology)GeneticsPolitical scienceLawMathematical analysisMathematicsCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsRNA regulation and disease