Litcius/Paper detail

TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation

Hao Xue, Bo Zhao, Martina Towers, Liping Liao, Edgar Luzete Monteiro, Xin Xu, Christina Freeman, Hongzhuang Peng, Hsin‐Yao Tang, Aaron Havas, Andrew V. Kossenkov, Shelley L. Berger, Peter D. Adams, David W. Speicher, D. Schultz, Ronen Marmorstein, Kenneth S. Zaret, Rugang Zhang

2024Nature Aging32 citationsDOIOpen Access PDF

Topics & Concepts

SenescenceInflammationProinflammatory cytokineInnate immune systemImmune systemBiologyPhenotypeCell biologyImmunologyCancer researchBiochemistryGeneinterferon and immune responsesRedox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms