Supersaturation and solvent dependent nucleation of carbamazepine polymorphs during rapid cooling crystallization
Jinbo Ouyang, Jian Chen, Ian Rosbottom, Wenqian Chen, Mingxia Guo, Jerry Y. Y. Heng
Abstract
The effects of interaction between the solvent and CBZ on solubility and polymorphic nucleation were discussed.
Topics & Concepts
SupersaturationNucleationCrystallizationSolubilitySolventMaterials scienceCarbamazepineChemical engineeringThermodynamicsChemistryPhysical chemistryOrganic chemistryPhysicsEngineeringNeuroscienceBiologyEpilepsyCrystallization and Solubility StudiesCrystallography and molecular interactionsThermal and Kinetic Analysis