Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase
Saif Ullah, Mohammed I. El–Gamal, Sumera Zaib, Hanan S. Anbar, Seyed–Omar Zaraei, Rawan M. Sbenati, Julie Pelletier, Jean Sévigny, Chang‐Hyun Oh, Jamshed Iqbal
Topics & Concepts
ChemistryPyrazoleThioureaDocking (animal)PhosphodiesteraseSulfonamideCombinatorial chemistryBiological activityBiochemistryStereochemistryEnzymeOrganic chemistryIn vitroNursingMedicineSynthesis and biological activityAdenosine and Purinergic SignalingSynthesis and Biological Evaluation