Engineering magnetotactic bacteria MVs to synergize chemotherapy, ferroptosis and immunotherapy for augmented antitumor therapy
Gexuan Jiang, Zhichu Xiang, Qiaojun Fang
Abstract
lung metastasis of tumor cells in a 4T1-Luc cell induced-lung breast cancer metastasis model. Collectively, the MVs-based nanoplatform offers an alternative promise for surmounting the limitations of monotherapy and may deserve further study for application in synergistic cancer therapy.
Topics & Concepts
Cancer researchImmunotherapyDoxorubicinImmune systemNanocarriersMagnetotactic bacteriaTumor microenvironmentMetastasisDrug deliveryCancerCancer cellChemotherapyChemistryMedicineBiologyDrugPharmacologyImmunologyBacteriaInternal medicineGeneticsOrganic chemistryBacteriophages and microbial interactionsBacterial Infections and VaccinesCancer Research and Treatments