pH-Responsive doxorubicin delivery using shear-thinning biomaterials for localized melanoma treatment
Junmin Lee, Yonggang Wang, Chengbin Xue, Yi Chen, Moyuan Qu, Jai Thakor, Xingwu Zhou, Natan Roberto de Barros, Natashya Falcone, Patric Young, Floor W. van den Dolder, KangJu Lee, Yangzhi Zhu, Hyun‐Jong Cho, Wujin Sun, Bo Zhao, Samad Ahadian, Vadim Jucaud, Mehmet R. Dokmeci, Ali Khademhosseini, Han‐Jun Kim
Abstract
Injectable shear-thinning biomaterials (STBs) have attracted significant attention because of their efficient and localized delivery of cells as well as various molecules ranging from growth factors to drugs.
Topics & Concepts
GelatinDoxorubicinMaterials scienceDrug deliveryIn vivoMelanomaCytotoxicityNanotechnologyBiophysicsIn vitroChemistryChemical engineeringBiomedical engineeringCancer researchChemotherapySurgeryOrganic chemistryBiochemistryBiologyEngineeringMedicineBiotechnology3D Printing in Biomedical ResearchCellular Mechanics and InteractionsHydrogels: synthesis, properties, applications