Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype

Samantha Medwid, Theodore J. Wigle, Richard B. Kim

2022Cancer Chemotherapy and Pharmacology21 citationsDOI

Topics & Concepts

DPYDDihydropyrimidine dehydrogenaseCapecitabineToxicityHaplotypeInternal medicineMedicinePharmacogeneticsLinkage disequilibriumDosingFluorouracilGenotypingPharmacologyGenotypeThymidylate synthaseOncologyChemotherapyBiologyCancerGeneticsColorectal cancerGeneColorectal Cancer Treatments and StudiesPancreatic and Hepatic Oncology ResearchBiochemical and Molecular Research

Fluoropyrimidine-associated toxicity and DPYD variants c.85T&gt;C, c.496A&gt;G, and c.1236G&gt;A: impact of haplotype

Topics & Concepts

Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype