CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity
Tingting Ye, Zifu Zhong, Federica Cappellesso, Kim Deswarte, Yong Chen, Heleen Lauwers, Emily De Lombaerde, Mark Gontsarik, Stefan Lienenklaus, Dorien Van Lysebetten, Niek N. Sanders, Bart N. Lambrecht, Stefaan De Koker, Damya Laoui, Bruno G. De Geest
Topics & Concepts
AgonistMaterials scienceNanoparticlePeptideLiposomePharmacologyBiophysicsNanotechnologyBiochemistryChemistryMedicineReceptorBiologyImmunotherapy and Immune ResponsesImmune Response and InflammationRNA Interference and Gene Delivery