Quizartinib plus chemotherapy in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia (QuANTUM-First): a randomised, double-blind, placebo-controlled, phase 3 trial
Harry P. Erba, Pau Montesinos, Hee‐Je Kim, Elżbieta Patkowska, Radovan Vrḫovac, Pavel Žák, Po‐Nan Wang, Tsvetomir Mitov, James Hanyok, Yasser Mostafa Kamel, Jaime E Connolly Rohrbach, Li Liu, Aziz Benzohra, Arnaud Lesegretain, Jörge E. Cortes, Alexander E. Perl, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Mark J. Levis, Richard F. Schlenk
Topics & Concepts
MedicineIdarubicinPlaceboInternal medicineCytarabineChemotherapy regimenInduction chemotherapyRegimenChemotherapySurgeryGastroenterologyPathologyAlternative medicineAcute Myeloid Leukemia ResearchProtein Degradation and InhibitorsMicrotubule and mitosis dynamics